My vote is to hook up the vacuum advance if simply for the fuel economy aspect that the additional ignition timing provides under cruising situations.  And be sure to put a set of lighter advance springs in the MSD distributor as it typically comes installed with the stiffest combination.  The various advance curve combinations are in both the enclosed instructions and on the outside of the box and reasonably easy to change.

And I’ll also suggest hooking the distributor up to the ported vacuum connection at the carb as connecting to a direct vacuum source makes for a rough idle, surging at low speed, and detonation at mid throttle without making major adjustments to the carburetor and distributor advance curves.  Direct and ported vacuum hookups at full throttle are both expected be a zero vacuum signal at the distributor.

The older models have a thin hex nut out on the nose of the can - if you remove it, you will find shims that adjust the spring preload. More preload - less vacuum advance.

Ooops.  My mistake.  Misread what you had and thought you had the MSD distributor also.  But still the same thoughts regarding the distributor vacuum advance hookup.