These guys know I like to "build my own" - its traditional car guy stuff - and you end up knowing a ton about it in the mean time - but this will boil down to the purpose you personally have in mind for the car/engine. If this is a race car - seldom streeted toy - I'd say grit your teeth, buy one from MSD (with a CD box) and be done with it.
If its a streeter - it needs to have vacuum advance and several good options exist:
(1) Buy a quality rebuilt - preferably the Motorcraft distributor based version - probably will come from the rebuilder Cardone. Ask for the part for a '64 F-100 w/ 292. It is easily fitted with a Pertronix Ignitor II or other "points replacement" trigger/controller so you have an electronic ignition. Coil choices may be limited depending on how "smart" the chip is or how much current the firing transistor can handle. Most of these will also work to trigger an MSD CD box.
(2) Use parts from a donor Duraspark II distributor (Ford V8 from '76 to '84) to modify the upper end of the Motorcraft rebuilt unit mentioned above - so it has a Ford electronic trigger assembly (the 8 blade reluctor). This is pretty much a parts change operation - not too complex. Then use it to trigger an MSD "red box" - or a Ford Duraspark II module - or a GM type HEI module. All can be made to work pretty well - the mechanical advance will need to be "curved" for this variant as well as (1) above.
(3) A company known as "DUI" can supply a Duraspark II based distributor unit - already built up as described above. It is then coupled to a controller that looks like a MOPAR part and fires an "E-core" coil that they also supply. Charlie McCraney has one and he has had good results with it I think.
Steve Metzger Tucson, Arizona