If you can adjust them, and the cup has adequate clearance between the rocker arm throughout the entire range of motion, then it really is not a problem.
Having the adjusters are far out as possible is beneficial because it gives you a larger ratio which means a little more lift and, I think, duration at the valve. This aspect could pose a problem since you are already so close to the limit.
The oil drip pans will give you extra room for adjustment but will alter the geometry which will affect the lift which may or may not put you beyond the .500 limit.
You can always put a dial indicator on a couple of the valves to verify the lift you are getting.
Another thing to be careful with is the rocker ratio used by a cam manufacturer to determine the actual lift. Often, it is 1.5:1. If you're using 1.54 or aftermarket 1.6 rockers, then you may already be over the .500 limit, particularly with the adjusters out and the increased ratio.
Further, the valve guides should have been machined for the increased lift. Were they? Make sure the retainer will not hit the guide.
Lawrenceville, GA