The boost typically added to a Y-block by a supercharger or turbo ultimately is not the issue, unless someone is going above 11-12 psi, measured at the supercharger outlet. The issue is horsepower. Your answer hits the nail on the head. As you increase boost, horsepower increases. If you add too much horsepower to an engine that is not made for it, you will break something. Elsewhere in this forum are some pictures by Ted Eaton of sbf engines that were built up to more horsepower than they can take.
My earlier comments about boost were made to provide some idea about how much air I need to run through the engine as one factor to consider in selecting headers.
I may have mentioned somewhere above that if you measure boost from the supercharger I plan to use, at about 6200 rpm it will show 11 to 12 psi at the blower outlet. If you measure the same pressure in the intake manifold, after various losses through the carbs, etc., you will see no more than 6 psi, maybe less. That is because of friction loss in the system. Typically, boost has traditionally been measured at the blower outlet, but measuring manifold pressure is a better indicator of what may be reaching the valves, where even more friction loss occurs as air flows through the head to the cylinder. I am not sure where you are measuring the tubo boost on the Powerstroke, but it is likely somewhere near where the air enters the head, thus 15 psi of boost on your diesel is probably equivalent to the 6-psi I would read in a Y-block manifold when the supercharger is putting out 11-12 psi at its outlet. If so, the diesel turbo is adding a lot more boost than I plan to add to a gas Y-block for street driving.
Getting back to the header issue, everyone seems to agree that going to more than 1-5/8 inch primary pipes on the header will cost low and mid-range power on a street car, even with the supercharger. I accept this, but I am not sure I understand exactly why this happens. Can anyone explain this?